Bullock plays a brilliant medical engineer Dr. Ryan Stone, first shuttle mission from their experienced astronaut Matt Kowalsky (Clooney) is passed - after this operation he wants to end his active service. However, during a seemingly normal spacewalk, it leads to disaster: The shuttle is destroyed - completely baseless until the bond between them spins Stone and Kowalsky completely alone in the darkness. Due to the deafening silence they know that they have lost contact with Earth ... and thus any chance of rescue. Her fear turns into panic, while every breath reduced their small supply of oxygen.